Kale and Artichoke Chicken Casserole









When you're looking for a wholesome, delicious, and comforting dinner that brings together nutrition and flavor, few dishes rival a well-made Kale and Artichoke Chicken Casserole. This hearty casserole is a twist on the classic spinach and artichoke dip—only more filling, protein-packed, and perfect for feeding a hungry family or meal-prepping for the week.

In this guide, you’ll learn how to make the perfect casserole, the health benefits of the ingredients, pro tips to elevate the dish, and a few delicious variations. Whether you're a beginner or a seasoned home cook, this recipe will quickly become a go-to in your kitchen.


Why You’ll Love This Recipe

  • Nutritious: Packed with lean protein, fiber, vitamins, and healthy fats.

  • Comforting: Creamy, cheesy, and satisfying—ideal for cool evenings.

  • Easy to Make Ahead: Prepare it earlier in the day or freeze it for future dinners.

  • Customizable: Easily swap ingredients to fit dietary needs or what you have on hand.


Ingredients

Here’s everything you’ll need for this rich and satisfying dish:

For the Chicken Casserole:

  • 2 tablespoons olive oil

  • 1 medium onion, diced

  • 3 cloves garlic, minced

  • 1 lb (450g) boneless, skinless chicken breasts or thighs, cooked and shredded

  • 4 cups chopped kale (ribs removed)

  • 1 (14 oz) can artichoke hearts, drained and chopped

  • 1 cup sour cream or Greek yogurt

  • 4 oz cream cheese, softened

  • 1/2 cup mayonnaise

  • 1 cup shredded mozzarella cheese

  • 1/2 cup grated Parmesan cheese

  • 1 teaspoon dried basil

  • 1/2 teaspoon salt

  • 1/2 teaspoon black pepper

  • 1/4 teaspoon red pepper flakes (optional)

For the Topping:

  • 1/2 cup panko breadcrumbs

  • 2 tablespoons melted butter

  • 1/4 cup Parmesan cheese (optional for extra crunch)


Instructions

Step 1: Prepare the Chicken

If not already cooked, season the chicken breasts with salt and pepper and bake at 375°F (190°C) for about 25 minutes, or until fully cooked. Shred and set aside.

Step 2: Sauté the Vegetables

In a large skillet, heat the olive oil over medium heat. Add the diced onions and cook until translucent, about 5 minutes. Stir in the garlic and cook for 1 more minute.

Add the chopped kale and cook until wilted, about 4-5 minutes. Remove from heat.

Step 3: Make the Creamy Base

In a large mixing bowl, combine the sour cream, cream cheese, and mayonnaise. Mix until smooth.

Stir in mozzarella cheese, Parmesan cheese, basil, salt, black pepper, and red pepper flakes.

Step 4: Assemble the Casserole

Fold in the shredded chicken, sautéed kale, and chopped artichokes into the creamy mixture.

Spread the mixture evenly into a greased 9x13-inch baking dish.

Step 5: Add the Crunchy Topping

In a small bowl, mix panko breadcrumbs with melted butter and Parmesan. Sprinkle evenly over the casserole.

Step 6: Bake

Preheat the oven to 375°F (190°C) and bake uncovered for 25–30 minutes, or until the casserole is hot and bubbly and the top is golden brown.

Step 7: Serve

Let the casserole rest for 5–10 minutes before serving. Pair it with a fresh salad, garlic bread, or roasted vegetables.


Nutritional Benefits

  • Chicken provides lean protein essential for muscle repair and satiety.

  • Kale is loaded with vitamins A, C, and K, plus fiber and antioxidants.

  • Artichokes add fiber, folate, and support liver health.

  • Greek yogurt or sour cream offer probiotics and creamy texture.

  • Olive oil adds heart-healthy fats.


Make It Healthier

  • Use Greek yogurt instead of sour cream for extra protein.

  • Swap cream cheese for low-fat ricotta for a lighter option.

  • Use reduced-fat cheese or half the cheese amount.

  • Add extra veggies like mushrooms, zucchini, or spinach.


Variations

Low-Carb Version:

Skip the panko topping and reduce the amount of cheese. This will keep the casserole keto-friendly.

Vegetarian Option:

Omit the chicken and replace it with chickpeas, white beans, or more veggies like mushrooms.

Spicy Kick:

Add diced jalapeños or a few dashes of hot sauce into the creamy base.

Make It Gluten-Free:

Use gluten-free panko or crushed gluten-free crackers for the topping.


Make Ahead and Freezing Tips

  • Make Ahead: Assemble the casserole up to the baking step. Cover and refrigerate for up to 24 hours.

  • Freeze: Cover tightly with plastic wrap and foil, then freeze for up to 2 months. Thaw overnight in the fridge before baking.

  • Reheat: Microwave individual portions or warm the entire casserole in the oven at 350°F until heated through.


Tips for Success

  • Use rotisserie chicken to save time.

  • Chop kale finely to help it blend well with other ingredients.

  • Drain artichokes well to prevent soggy casserole.

  • Let it rest before cutting—this helps the casserole set for neater portions.


What to Serve With Kale and Artichoke Chicken Casserole

  • Crusty bread or garlic toast

  • Side salad with vinaigrette

  • Steamed broccoli or green beans

  • Roasted sweet potatoes or carrots


Frequently Asked Questions

Q: Can I use frozen kale or spinach?
Yes! Just thaw and squeeze out the moisture before using.

Q: What if I don’t have artichokes?
Substitute with sautéed mushrooms, zucchini, or omit entirely.

Q: Can I use canned chicken?
You can, though the texture of freshly cooked or rotisserie chicken is preferable.

Q: How long will leftovers last?
Up to 4 days in the refrigerator when stored in an airtight container.


Final Thoughts

This Kale and Artichoke Chicken Casserole is more than just a warm, creamy dinner—it’s a balanced meal that pleases both taste buds and health goals. With options to adapt it to your preferences, this dish is a versatile staple you'll come back to over and over again.

Whether you’re cooking for a crowd or meal-prepping for the week, this casserole is sure to impress. Serve it up hot, bubbly, and packed with love—and don’t forget to save the leftovers (if there are any!). 

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